Monday, July 15, 2019

Suninat 50mg Capsules| Sunitinib Uses & Side effects


                             SUNINAT 50MG


DESCRIPTION

       Suninat 50mg  is sold under the Suninat 50mg capsules brand nameSuninat 50mg  Suninat which is needed to treat a gastrointestinal stromal tumor (GIST) after other medicines (e.g., imatinib) did not work very well.

Suninat 50mg capsules belongs to the Suninat 50mg capsules  group of medicines Suninat 50mg capsules  known as antitumorSuninat 50mg  medication. It prevents Suninat 50mg the development of cancer cells, which are eventually damaged.

Suninat 50mg  is a prescription drugsSuninat 50mg capsules  which is used under Suninat 50mg  the guidance of medical practioners
suninat 50mg capsules
suninat 50mg

INDICATION

Suninat 50mg capsules is prescribed Suninat 50mg for the therapy of advancedSuninat 50mg capsules  renal cell carcinoma as well as the treatment ofSuninat 50mg capsules  gastrointestinal stromal tumor after disease progression Suninat 50mg capsules  on orSuninat 50mg  intolerance to imatinib mesylate.

MECHANISM OF ACTION

SunitinibSuninat 50mg  shows antitumor andSuninat 50mg capsules  antiangiogenic properties by prohibiting multiple receptor Suninat 50mg capsules tyrosine kinases, Suninat 50mg containing platelet-derived growth factors (PDGFRα and PDGFRβ), vascular endothelial growth factorsSuninat 50mg capsules  (VEGFR1, VEGFR2, and VEGFR3), Suninat 50mg capsules FMS-like tyrosine kinase-3 (FLT3), colony-stimulating factor type 1 (CSF-1R), and glial cell-line-derived neurotrophic factor receptor (RET).

PRODUCT DETAILS

Brand :Suninat

Ingredients : Sunitinib

Strength : 50mg

Manufactured : Natco Pharma Ltd

Package : 28 capsules in a bottle
PRICE:Suninat 50mg ,Suninat 50mg capsules 
  ADME

Duration of maximumSuninat 50mg capsules  plasma concentration Suninat 50mg capsules of sunitinib is between 6 and 12 hours 

High Suninat 50mg protein binding was 95 % and Suninat 50mg 90 % respectively. 

Mainly metabolized by Suninat 50mg capsules cytochrome P450 enzyme, CYP3A4 

EliminationSuninat 50mg capsules  of Suninat mainlyviaSuninat 50mg capsules  feces 61% and renal excretion is 16% of administrated dose.

Sunitinib half-life is 40 – 60 hours 

Mainly active metaboliteSuninat 50mg capsules  half-life was Suninat 50mg capsules  80 – 110 hours

DOSAGE MANAGEMENT





 The prescribed dose for Suninat 50mg capsules  Gastrointestinal Stromal Suninat 50mg capsules Tumor is 50 mg PO qDay for 4 weeks, continued by 2 weeks drug-free, repeat cycle.
The prescribed dose for Renal Cell Suninat 50mg capsules  Carcinoma is 50 mg PO qDay for 4 weeks, followed Suninat 50mg capsules by 2 weeks drug-free, repeat cycle.
Adjuvant treatment of RCC :
• Prescribed for the adjuvant therapySuninat 50mg capsules  of adult patients at Suninat 50mg capsules maximum risk of relapsed RCC following nephrectomy
• The PrescribedSuninat 50mg capsules  dose is 50 mg PO qDay for 4 weeks,Suninat 50mg  continued by 2 weeks drug-free, repeat cycle for a maximum of nineSuninat 50mg capsules  6-week cycles totally
Pancreatic Neuroendocrine Tumor :
Necessary for progress,Suninat 50mg capsules  well-differentiated Suninat 50mg capsules pancreatic neuroendocrine tumor (pNET) in patients with unresectable locally advanced or metastatic disease
The prescribed doseSuninat 50mg  for Pancreatic NeuroendocrineSuninat 50mg capsules  Tumor is 37.5 mg PO qDay continuously without a scheduled off-treatment period

PRECAUSION

• While using of Suninat 50mg capsules, Hypothyroidism occurred;Suninat 50mg capsules check the baseline thyroid function in patients withSuninat 50mg  hypothyroidism or hyperthyroidism and treat per standard medical practice before to initiating treatment
• While using of Suninat 50mg capsules will have ImpairedSuninat 50mg capsules  wound healing resulted; temporary interfere with treatment recommended if go through major surgical procedures
• When treatment Suninat Suninat 50mg capsules  50mg will causes severeSuninat 50mg capsules  hepatotoxicity involving liver failure; checkSuninat 50mg  liver function tests before starting treatment.
• When treatment Suninat 50mg Haemorrhagic events involving tumor-related haemorrhage resulted; test the serial complete blood counts and physical examinations
• When Suninat 50mg capsules  treatment Suninat 50mg, Adrenal haemorrhage occurredSuninat 50mg capsules  in animal studies; check the adrenal function in case of Suninat 50mg capsules stress such as surgery, trauma or severe infection
• While on treatment Suninat 50mg capsules  with Suninat 50mg  Suninat 50mg, regulateurine protein; prohibit treatment for 24-hr urine protein ≥3 g; discontinue for repeat episodes of proteinSuninat 50mg capsules  ≥3 g despite dose reductions or nephrotic syndrome

SIDE EFFECT


Common side effects :

Hives, Breathing difficultySuninat 50mg capsules , Sore throat, Suninat 50mg Skin pain,Suninat 50mg capsules  Red or Purple skin rash Upper stomach pain, Itching, Tried feeling, Suninat 50mg capsules Decreased appetite,Suninat 50mg capsules   Dark urine, Jaundice.

Serious side effects :

Tiredness, decreasedSuninat 50mg capsules  urination, Slow heart rate.Suninat 50mg capsules  Thyroid problem Swelling in Suninat 50mg capsules ankles or feet, Shortness of breath, Unusual bruising, Muscle Suninat 50mg  cramps, Fast heart beats, Sudden dizziness

EMAIL ID     : millionhealthpharmaceuticals@gmail.com
PHONE NO   : +91-9940472902

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